Review Article CODEN: IJPNL6 AN OVERVIEW ON RECENT ADVANCES AND CURRENT TRENDS IN ORAL MUCOADHESIVE DRUG DELIVERY SYSTEM

Buccal administration of drugs provides a convenient route of administration for both systemic and local drug actions. The major hindrance for the absorption of a drug taken orally is extensive first pass metabolism or stability problems within the GI environment like instability in gastric pH and complexation with mucosal membrane. In both the stimulation of these types of buccal drugs start info, mucoadhesion of system is a key component. Mucoadhesive polymers make been used beneath lots additional dosage variety beneath work to achieve systemic start on medication on both the buccal mucosa. It is also possible to administer drugs to the patients of subconscious and bless co-operative. In order to prevent accidental swallowing on drugs epoxy mucosal dosage variety were meant for oral start, which included epoxy tablets, movies, greases, other dosage variety with various mixtures of polymers, absorption enhancers. Several methodologies have been considered so far, to design and manipulate the release properties towards the invention of buccal mucosal delivery systems