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The aim of the present study was to evaluate the Invitro Antioxidant and neuropharmacological parameters of the Ethanolic leaf extract of Ficus racemosa against stress induced amnesia in Albino rats. Nootropics are agents that enhance the cognitive skills. Learning and memory can be conceived as both a psychological process, as well as a change in synaptic neural connectivity. In vitro antioxidant activity was evaluated using the parameters such as Nitric oxide-scavenging activity, Hydrogen peroxide scavenging and Hydroxyl radical scavenging. Ascorbic acid with same concentration was used as a standard antioxidant. In the present study the extract (150 and 300 mg/kg, p.o) was investigated for Nootropic activity in normal and stress induced rats. Conditioned avoidance response using Cook’s pole climbing apparatus and transfer latency using elevated plus maze were used in normal and stress induced rats to assess cognitive-improvin