Abstract. High throughput platforms available in clinical settings or in research laboratories, such as magnetic resonance imaging, microarray, mass spectrometry and next-generation sequencing, are producing an increasing volume of clinical and omics data that poses new issues in terms of secure data storage, models for data integration and analysis, and high performance computing. Cloud Computing offers large scalable computing and storage, data sharing, on-demand anytime and anywhere access to resources and applications, and it supports easy but powerful distributed computing models, for facing those issues. In fact, in the recent years it has been adopted for the deployment of several applications in healthcare and bioinformatics both in...