Postgraduate Education Corner CONTEMPORARY REVIEWS IN SLEEP MEDICINE CHEST 1394 Postgraduate Education Corner

Travel is a part of everyday life for most individ-uals. Long-distance air travel is quite common and increas ing in frequency. In 2010, 787 million passen-gers traveled by plane in the United States (domestic and international). International travel on both US and foreign carriers increased by 3.2 % from 2009 to 2010. 1 During long-distance travel, sleep is frequently dis-rupted, and the ensuing sleep deprivation plays a cen-tral role in the clinical manifestations of both travel fatigue and jet lag disorder (JLD). In this article, we hope to increase the reader’s understanding of the neurocognitive manifestations of acute sleep depriva-tion and the basic mechanisms of circadian regula-tion to elucidate the manifestations and therapeutic options in the management of JLD. Sleep Deprivatio