Do Flavonoid Intakes of Postmenopausal Women With Breast Cancer Vary on Very Low Fat Diets?

In the Women’s Intervention Nutrition Study (WINS), a very low-fat eating pattern decreased breast cancer recurrence. We assessed whether the women’s flavonoid intakes varied on the very low fat diet. A total of 550 randomly selected WINS partic-ipants who had been treated with conventional therapy (surgery, chemotherapy, and/or radiation) for primary breast cancer were randomized to either a very low fat diet (15 % of calories from fat, N = 218) or their usual diets (30 % calories from fat, N = 332). We compared their intakes of total flavonoids and 6 flavonoid classes (isoflavones, flavones, flavanones, flavonols, flavan-3-ols, and an-thocyanins) for these 2 groups using the U.S. Department of Agri-culture food flavonoid database and a flavonoid dietary supplement database on three 24-h dietary recalls at baseline and 12 mo after randomization. At baseline, neither mean fat intakes (31.7 % ± 6.8 SD of calories, n = 332 in the usual diet group and 31.6 % ± 6.