Study on Protective Effect of Omega-3 Fatty Acid Rich Extract of Linium Usitatissimum Seeds on Cisplatin Induced Nephrotoxicity

There are many diseases that are still considered as untreatable by most of the physicians, and epilepsy is one of those. Traditional healers claim that they can treat epilepsy by use of some natural components. The Indian Traditional Medicine like Ayurveda, Siddha and Unani are predominantly based on the use of herbal drugs/ products for medicinal benefits. Herbal drugs have gained importance and popularity in recent years because of their safety, efficacy and cost effectiveness. One of the important and well-documented uses of plant products is their use as nephro-protective agents. Hence, there is an ever increasing need for safe nephro-protective agent. Oxidative stress is a state where oxidative forces exceed the antioxidant systems due to loss of the balance between them. Thus due to easy availability of plant and its traditional uses, the present study was designed to investigate the effect of plant extract against Cisplatin induced nephrotoxicity in rats by using biochemical parameters and antioxidant status in kidney of rats after oral administration of 100 and 200 mg / kg body weight of extract