OF PROCESSES

Proteomics techniques have been used to generate com-prehensive lists of protein interactions in a number of species. However, relatively little is known about how these interactions result in functional multiprotein com-plexes. This gap can be bridged by combining data from proteomics experiments with data from established structure determination techniques. Correspondingly, in-tegrative computational methods are being developed to provide descriptions of protein complexes at varying lev-els of accuracy and resolution, ranging from complex compositions to detailed atomic structures. Molecular & Cellular Proteomics 9:1689–1702, 2010. A 3-D enhanced version of this article is available. The text is identical to this version but includes interactive figures. Viewing the enhanced version of this article requires the use of a browser plug-in. Please install the plug-in when prompted