1.1 ALS and SOD1 In 1993, a genetic link was established between amyotrophic lateral sclerosis (ALS) and mutant forms of Cu,Zn superoxide dismutase (SOD1) (Deng et al. 1993; Rosen et al. 1993), an antioxidant enzyme that catalyzes the dismutation of the damaging free radica
Proteins are the most important molecules in the cell since they take care of most of the biological...
Mutations of Cu, Zn‐superoxide dismutase (SOD1) gene have been identified in a subset of familial am...
Many mutations confer upon copper/zinc superoxide dismutase-1 (SOD1) one or more toxic function(s) t...
AbstractFourteen years after the discovery that mutations in Cu, Zn superoxide dismutase (SOD1) caus...
Cu, Zn superoxide dismutase (SOD1) is a dimeric metal binding enzyme responsible for the dismutation...
Amyotrophic lateral sclerosis (ALS) is a disease in which the motor neurons die in a progressive man...
Amyotrophic lateral sclerosis (ALS) is characterized by motor neuron degeneration resulting in progr...
Amyotrophic lateral sclerosis (ALS) is a progressive paralytic disease characterized by selective de...
There are about 100 single point mutations of copper, zinc superoxide dismutase 1 (SOD1) which are r...
The underlying cause of amyotrophic lateral sclerosis (ALS), a progressive neurodegenerative disease...
Amyotrophic lateral sclerosis (ALS) is a fatal degenerative disease of motor neurons. About 10 % of ...
Amino acid replacements at dozens of positions in the dimeric protein human, Cu,Zn superoxide dismut...
International audienceBackground: Copper/zinc superoxide dismutase (SOD1) genetic mutants are associ...
Amyotrophic lateral sclerosis (ALS) is a paralytic disorder caused by degeneration of motor neurons ...
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease causing degeneration of upper and...
Proteins are the most important molecules in the cell since they take care of most of the biological...
Mutations of Cu, Zn‐superoxide dismutase (SOD1) gene have been identified in a subset of familial am...
Many mutations confer upon copper/zinc superoxide dismutase-1 (SOD1) one or more toxic function(s) t...
AbstractFourteen years after the discovery that mutations in Cu, Zn superoxide dismutase (SOD1) caus...
Cu, Zn superoxide dismutase (SOD1) is a dimeric metal binding enzyme responsible for the dismutation...
Amyotrophic lateral sclerosis (ALS) is a disease in which the motor neurons die in a progressive man...
Amyotrophic lateral sclerosis (ALS) is characterized by motor neuron degeneration resulting in progr...
Amyotrophic lateral sclerosis (ALS) is a progressive paralytic disease characterized by selective de...
There are about 100 single point mutations of copper, zinc superoxide dismutase 1 (SOD1) which are r...
The underlying cause of amyotrophic lateral sclerosis (ALS), a progressive neurodegenerative disease...
Amyotrophic lateral sclerosis (ALS) is a fatal degenerative disease of motor neurons. About 10 % of ...
Amino acid replacements at dozens of positions in the dimeric protein human, Cu,Zn superoxide dismut...
International audienceBackground: Copper/zinc superoxide dismutase (SOD1) genetic mutants are associ...
Amyotrophic lateral sclerosis (ALS) is a paralytic disorder caused by degeneration of motor neurons ...
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease causing degeneration of upper and...
Proteins are the most important molecules in the cell since they take care of most of the biological...
Mutations of Cu, Zn‐superoxide dismutase (SOD1) gene have been identified in a subset of familial am...
Many mutations confer upon copper/zinc superoxide dismutase-1 (SOD1) one or more toxic function(s) t...