Background: Enzyme-linked immunospot (ELISpot) assay is an in-creasingly widely used, T-cell–based, interferon-–release assay for diagnosing tuberculosis infection, but whether positive results are prognostic of active tuberculosis is not known. Objective: To determine whether ELISpot results predict the devel-opment of active tuberculosis among persons with recent tubercu-losis exposure. Design: Longitudinal cohort study of children and adolescents with tuberculosis contact recruited from October 2002 to April 2004. Setting: Community-based contact investigations in Turkey. Patients: 908 children and adolescents with recent household tu-berculosis exposure. Intervention: Enzyme-linked immunospot assay, incorporating early secretory antigen...
Background: Children have an increased risk of developing active tuberculosis (TB) after exposure to...
Interferon-γ-based assays, collectively known as IFN-γ release assays (IGRAs), have emerged as a rel...
Background: Interferon-γ assays based on tuberculosis (TB)-specific antigens have been utilized for ...
Background: Enzyme-linked immunospot (ELISpot) assay is an increasingly widely used, T-cell-based, i...
infection, yet immune responses to only two gene-products, Early Secretory Antigenic Target-6 (ESAT...
Chemoprophylaxis of contacts of infectious tuberculosis (TB) cases is recommended for TB control, pa...
Rationale: Interferon-gamma release assays are widely used to diagnose latent infection with Mycobac...
BackgroundTackling tuberculosis requires testing and treatment of latent tuberculosis in high-risk g...
BACKGROUND: Although currently available IGRA have been reported to be promising markers for TB infe...
Background Tackling tuberculosis (TB) requires testing and treatment latent tuberculosis in high-ris...
Chemoprophylaxis of contacts of infectious tuberculosis (TB) cases is recommended for TB control, pa...
The interferon-gamma enzyme-linked immunospot assay (ELISPOT ) has been demonstrated to be useful in...
Mycobacterium tuberculosis Region-of-Difference-1 gene products present opportunities for specific d...
Rationale: Biomarkers that can be used to evaluate new interventions against latent tuberculosis inf...
Background. Currently, reliable efficacy markers for assessment of new interventions against tubercu...
Background: Children have an increased risk of developing active tuberculosis (TB) after exposure to...
Interferon-γ-based assays, collectively known as IFN-γ release assays (IGRAs), have emerged as a rel...
Background: Interferon-γ assays based on tuberculosis (TB)-specific antigens have been utilized for ...
Background: Enzyme-linked immunospot (ELISpot) assay is an increasingly widely used, T-cell-based, i...
infection, yet immune responses to only two gene-products, Early Secretory Antigenic Target-6 (ESAT...
Chemoprophylaxis of contacts of infectious tuberculosis (TB) cases is recommended for TB control, pa...
Rationale: Interferon-gamma release assays are widely used to diagnose latent infection with Mycobac...
BackgroundTackling tuberculosis requires testing and treatment of latent tuberculosis in high-risk g...
BACKGROUND: Although currently available IGRA have been reported to be promising markers for TB infe...
Background Tackling tuberculosis (TB) requires testing and treatment latent tuberculosis in high-ris...
Chemoprophylaxis of contacts of infectious tuberculosis (TB) cases is recommended for TB control, pa...
The interferon-gamma enzyme-linked immunospot assay (ELISPOT ) has been demonstrated to be useful in...
Mycobacterium tuberculosis Region-of-Difference-1 gene products present opportunities for specific d...
Rationale: Biomarkers that can be used to evaluate new interventions against latent tuberculosis inf...
Background. Currently, reliable efficacy markers for assessment of new interventions against tubercu...
Background: Children have an increased risk of developing active tuberculosis (TB) after exposure to...
Interferon-γ-based assays, collectively known as IFN-γ release assays (IGRAs), have emerged as a rel...
Background: Interferon-γ assays based on tuberculosis (TB)-specific antigens have been utilized for ...
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