both the Maternal Fetal Medicine and Infectious Diseases

Objectives: (1) To review the effects of parvovirus B19 on the pregnant woman and fetus, and (2) to discuss the management of women who are exposed to, who are at risk of developing, or who develop parvovirus B19 infection in pregnancy. Outcomes: Maternal outcomes of parvovirus B19 including ery-thema infectiosum, arthropathy, anemia, and myocarditis. Fetal outcomes including spontaneous abortion, congenital anom-alies, hydrops fetalis, stillbirth, and long-term effects. Evidence: MEDLINE search from 1966 to January 2002 for arti-cles relating to parvovirus B19 infection, using key words “parvovirus ” and “pregnancy, ” and guidelines of professional organizations including the American College of Obstetricians and Gynecologists