,b, hys

rea bin solved in two crystal forms (P42212 and P3121) diffracting to 3.0 and 2.3 A resolution, respectively. The structures are similar to the precorrin-8x methyl mutase (CobH), an enzyme of the aerobic pathway to vitamin B12. 2005 Elsevier Inc. All rights reserved. tists have enzymes that require cobalamin as cofactor, intermediates on the anaerobic pathway are known. The two pathways are broadly similar (Roth et al., 1993). has small differences in surrounding of cobalt-precorrin 8 binding. The CbiC_LEPIN structure will provide clues for understanding the function of CbiC/CobH family in the biosynthesis pathway. * Corresponding author