Compensatory hypertrophy

Nephron segments X-ray microanalysis OOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOO The compensatory hypertrophy in different renal cortical structures was stud-ied in rats 10 and 21 days after unilateral nephrectomy (UNX). Quantitative morphological/stereological analysis revealed significant increases in total renal cortical volume – 33 % on day 10 and 48 % on day 21 – after UNX. These changes were paralleled by significant increments in the volumes of proximal convoluted tubule (PCT, 55%), distal convoluted tubule (DCT, 114%), and cortical collecting duct (CCD, 106%) segments on day 10. The corresponding changes on day 21 were 76, 122, and 212%, respectively. These alterations were accompanied by increases in segment length; 3 % PCT, 23 % DCT, and 50 % CCD on day 10 and 9 % PCT, 30 % DCT, and 142 % CCD on day 21 after UNX. The total luminal and basolateral cell membrane surface areas als