Add to ORKGWe have analyzed the interrelationships between habitual alcohol consumption, peak blood alcohol concentration after a standard dose, and rate of alcohol metabolism in a group of 199 male and 213 female twins. Both peak concentration and rate of metabolism are strongly associated with alcohol consumption levels, even in the range of 0-10 g of alcohol/day. The peak concentration and rate of metabolism were strongly correlated in both men and women; this is not due to their common dependence on alcohol intake nor to experimental error. These results show that the threshold for effects of habitual consumption on alcohol pharmacokinetics is much lower than previously suspected, and that there are factors that reduce preabsorptive or first-pass ...
The absorption rate of alcohol is one of the determinants of the peak blood alcohol concentration. S...
As Gibson and Oakeshottl • 2 indicated earlier in this volume, a wide range of biochemical and behav...
The pharmacokinetics (PK) of ethanol are important in pharmacology and therapeutics because of poten...
It is a common observation that individuals differ greatly in their consumption of alcohol and in th...
alcohol-dependence risk, demonstrated in both Asian and non-Asian populations, suggests a link betwe...
Abstract: It is a common observation that individuals differ greatly in their consumption of alcohol...
Background: The significant association between alcohol dehydrogenase (ADH)-2 genotype and alcohol-d...
ABSTRACT. Ge"netic models were filled to self-report data on fre-quency of alcohol consumption ...
It Is a commonplace observation that some people are greatly affected by even small doses of alcohol...
A battery of psychomotor tasks and physiological measures was admin-istered to 206 pairs of twins be...
The present analyses examined genetic influences on alcohol metabolism and their possible rela-tions...
It is a common observation that individuals differ greatly in their consumption of alcohol and, if t...
BACKGROUND: In the past two decades, the metabolic syndrome has given rise to much clinical and rese...
ABSTRACT. We reanalyzed data on the decline in performance on a battery of psychomotor tests, after ...
Women appear to become more impaired than men after drinking equivalent amounts of alcohol, achievin...
The absorption rate of alcohol is one of the determinants of the peak blood alcohol concentration. S...
As Gibson and Oakeshottl • 2 indicated earlier in this volume, a wide range of biochemical and behav...
The pharmacokinetics (PK) of ethanol are important in pharmacology and therapeutics because of poten...
It is a common observation that individuals differ greatly in their consumption of alcohol and in th...
alcohol-dependence risk, demonstrated in both Asian and non-Asian populations, suggests a link betwe...
Abstract: It is a common observation that individuals differ greatly in their consumption of alcohol...
Background: The significant association between alcohol dehydrogenase (ADH)-2 genotype and alcohol-d...
ABSTRACT. Ge"netic models were filled to self-report data on fre-quency of alcohol consumption ...
It Is a commonplace observation that some people are greatly affected by even small doses of alcohol...
A battery of psychomotor tasks and physiological measures was admin-istered to 206 pairs of twins be...
The present analyses examined genetic influences on alcohol metabolism and their possible rela-tions...
It is a common observation that individuals differ greatly in their consumption of alcohol and, if t...
BACKGROUND: In the past two decades, the metabolic syndrome has given rise to much clinical and rese...
ABSTRACT. We reanalyzed data on the decline in performance on a battery of psychomotor tests, after ...
Women appear to become more impaired than men after drinking equivalent amounts of alcohol, achievin...
The absorption rate of alcohol is one of the determinants of the peak blood alcohol concentration. S...
As Gibson and Oakeshottl • 2 indicated earlier in this volume, a wide range of biochemical and behav...
The pharmacokinetics (PK) of ethanol are important in pharmacology and therapeutics because of poten...