Maturitas 33 (1999) S65–S72 HRT and cancer risk: separating fact from fiction

Introduction and methods: The benefits of hormone replacement therapy (HRT) in postmenopausal women are well known including control of vasomotor symptoms and long-term benefits on the cardiovascular, skeletal and central nervous systems. However, some studies have reported a link between long-term HRT use and cancer. This paper reviews some of the data related to HRT and major gynaecological cancers. Results: Appropriate HRT regimens can reduce the risk of endometrial hyperplasia in non-hysterectomised women and can reduce the incidence of colorecta