International Journal of Health Sciences and Research www.ijhsr.org ISSN: 2249-9571

Ameloblastoma is a true neoplasm of odontogenic epithelial origin. It is the second most common odontogenic neoplasm, and only odontoma outnumbers it in reported frequency of occurrence. Its incidence, combined with its clinical behavior, makes ameloblastoma the most significant odontogenic neoplasm. Unicystic ameloblastoma (UA) refers to those cystic lesions that show clinical, radiographic, or gross features of a mandibular cyst, but on histologic examination shows a typical ameloblastomatous epithelium lining part of the cyst cavity, with or without luminal and/or mural tumor growth. It accounts for 5-15 % of all intraosseousameloblastomas. Unicystic ameloblastoma is a less encountered variant of the ameloblastoma and believed to be less aggressive. Moreover, recurrence of unicysticameloblastoma may be long delayed and a long-term post-operative follow up is essential for proper management of these patients. In this case report we present a uncommon multilocularunicystic ameloblastoma encountered in a 40 year old male patient