Add to ORKGThis study was aimed at investigating the effects of lamotrigine (LTG) on electrically evoked field excitatory postsynaptic potentials (fEPSP) and population spikes in the CA1 hippocampal region of guinea pigs. The concen-tration response curves showed different actions of LTG on fEPSP and on population spikes. The data are in con-trast to previous findings that suggest the drug acts pri-marily on presynaptic sites via a blockade of the release of excitatory amino acids. In the range of therapeutic plasma levels, synaptic transmission was not affected. Copyright © 2000 S. Karger AG, Base
Background/Aims: Lamotrigine (LTG) is a popular modern antiepileptic drug (AED), however, its mechan...
The combination of transcranial magnetic stimulation and electroencephalography (TMS-EEG) has uncove...
The combination of transcranial magnetic stimulation and electroencephalography (TMS-EEG) has uncove...
This study was aimed at investigating the effects of lamotrigine (LTG) on electrically evoked field ...
Lamotrigine (LTG) is generally considered as a voltage-gated sodium (Nav) channel blocker. However, ...
There is compelling evidence to suggest that epileptic seizures may be associated with neurochemical...
Contains fulltext : 200825.pdf (Publisher’s version ) (Open Access)Objective: The ...
We studied the action of the new antiepileptic drugs lamotrigine (LTG), GP 47779 (the active metabol...
We performed intracellular recordings from a rat corticostriatal slice preparation in order to compa...
1. Little information is available about the action of lamotrigine (LTG) on EEG paroxysmal abnormali...
Sipatrigine (BW619C89), a derivative of the antiepileptic agent lamotrigine, has potent neuroprotect...
Actions of the new antiepileptic drug lamotrigine (LTG) were characterized using extracellular and w...
Background/Aims: Lamotrigine (LTG) is a popular modern antiepileptic drug (AED), however, its mechan...
The combination of transcranial magnetic stimulation and electroencephalography (TMS-EEG) has uncove...
The combination of transcranial magnetic stimulation and electroencephalography (TMS-EEG) has uncove...
This study was aimed at investigating the effects of lamotrigine (LTG) on electrically evoked field ...
Lamotrigine (LTG) is generally considered as a voltage-gated sodium (Nav) channel blocker. However, ...
There is compelling evidence to suggest that epileptic seizures may be associated with neurochemical...
Contains fulltext : 200825.pdf (Publisher’s version ) (Open Access)Objective: The ...
We studied the action of the new antiepileptic drugs lamotrigine (LTG), GP 47779 (the active metabol...
We performed intracellular recordings from a rat corticostriatal slice preparation in order to compa...
1. Little information is available about the action of lamotrigine (LTG) on EEG paroxysmal abnormali...
Sipatrigine (BW619C89), a derivative of the antiepileptic agent lamotrigine, has potent neuroprotect...
Actions of the new antiepileptic drug lamotrigine (LTG) were characterized using extracellular and w...
Background/Aims: Lamotrigine (LTG) is a popular modern antiepileptic drug (AED), however, its mechan...
The combination of transcranial magnetic stimulation and electroencephalography (TMS-EEG) has uncove...
The combination of transcranial magnetic stimulation and electroencephalography (TMS-EEG) has uncove...