Original Research Article Alloimmunisation of Red Blood Cells in Multitransfused Patients

This study was carried at Acharya Vinoba Bhave rural hospital Sawangi [Meghe] in patients having blood transfusion reactions to determine the incidence of alloimmunisation against red cell antigens in multiple blood transfusions. Antibody screening was performed in thalassemia group of patients, including sickle cell disease, and chronic renal failure patents where hemodialysis is required frequently. Regrouping and re-cross matching was performed using various standard methods. It was observed that antibodies were highest in thalassemias in 50 % of cases, and sickle cell disease and chronic renal failure in 25 % of cases respectively