Abstract: The search for effective strategies for peripheral nerve regeneration has attracted much attention in recent years. In this study, ordered collagen fibers were used as intraluminal fibers after nerve injury in rats. Vascular endothelial growth factor (VEGF) plays an important role in nerve regeneration, but its very fast initial burst of activity within a short time has largely limited its clinical use. For the stable binding of VEGF to ordered collagen fibers, we fused a collagen-binding domain (CBD) to VEGF through recombinant DNA technology. Then, we filled the ordered collagen fibers-CBD-VEGF targeting delivery system in a collagen tube to construct natural neural scaffolds, which were then used to OPEN ACCESS Int. J. Mol. Sci...
The development of effective treatments for patients with peripheral nerve injury is an urgent task ...
Despite the success of tissue engineered nerve guidance conduits (NGCs) for the treatment of small p...
Despite the success of tissue engineered nerve guidance conduits (NGCs) for the treatment of small p...
The search for effective strategies for peripheral nerve regeneration has attracted much attention i...
The search for effective strategies for peripheral nerve regeneration has attracted much attention i...
The development of effective treatments for patients with peripheral nerve injury is an urgent task ...
We studied regeneration of rat sciatic nerve while overcoming of a 5-mm diastasis with the aid of na...
【Abstract】Objective: To evaluate the local effect of vascular endothelial growth factor (VEGF) on t...
Peripheral nerve injuries often result in lifelong disabilities despite advanced surgical interventi...
Peripheral nerve regeneration requires stepwise and well-organized establishment of microenvironment...
Collagen nerve guides are used clinically for peripheral nerve defects, but their use is generally l...
Collagen nerve guides are used clinically for peripheral nerve defects, but their use is generally l...
The use of autologous nerve grafts remains the gold standard for treating nerve defects, but current...
The development of effective treatments for patients with peripheral nerve injury is an urgent task ...
<span lang="EN-US" style="font-family: "Calibri","sans-serif"; font-size: 10.5pt...
The development of effective treatments for patients with peripheral nerve injury is an urgent task ...
Despite the success of tissue engineered nerve guidance conduits (NGCs) for the treatment of small p...
Despite the success of tissue engineered nerve guidance conduits (NGCs) for the treatment of small p...
The search for effective strategies for peripheral nerve regeneration has attracted much attention i...
The search for effective strategies for peripheral nerve regeneration has attracted much attention i...
The development of effective treatments for patients with peripheral nerve injury is an urgent task ...
We studied regeneration of rat sciatic nerve while overcoming of a 5-mm diastasis with the aid of na...
【Abstract】Objective: To evaluate the local effect of vascular endothelial growth factor (VEGF) on t...
Peripheral nerve injuries often result in lifelong disabilities despite advanced surgical interventi...
Peripheral nerve regeneration requires stepwise and well-organized establishment of microenvironment...
Collagen nerve guides are used clinically for peripheral nerve defects, but their use is generally l...
Collagen nerve guides are used clinically for peripheral nerve defects, but their use is generally l...
The use of autologous nerve grafts remains the gold standard for treating nerve defects, but current...
The development of effective treatments for patients with peripheral nerve injury is an urgent task ...
<span lang="EN-US" style="font-family: "Calibri","sans-serif"; font-size: 10.5pt...
The development of effective treatments for patients with peripheral nerve injury is an urgent task ...
Despite the success of tissue engineered nerve guidance conduits (NGCs) for the treatment of small p...
Despite the success of tissue engineered nerve guidance conduits (NGCs) for the treatment of small p...