Separation of Ascorbic Acid, Dopamine and Uric Acid by Acetone/Water Modified Carbon Paste Electrode: A Cyclic Voltammetric Study

The carbon paste (CPE) was prepared by grinding the mixture of graphite powder and silicone oil ratio 70:30 respectively. The acetone/water modified carbon paste electrode was developed by immobilizing the different ratios of acetone/water. The best ratio was 20:80 acetone/water respectively. The peak currents in voltammogram of dopamine was increased at acetone/water modified carbon paste electrode when compared to bare CPE. The effect of substrate concentration, ratio of acetone/water and scan rate were studied. The electrode process was found to be diffusion controlled. The acetone/water modified carbon paste electrode showed selective enhancement of oxidation peak current for DA in the presence of ascorbic acid (AA) and uric acid (UA)