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Subject In reference to the above, I as a corresponding author, I am submitting this manuscript for publication in International Journal of Applied Sciences and Biotechnology (IJASBT). This manuscript has not been published or communicated for publication in any other journal or elsewhere. I have undertaken the prior approval of country/institutional ethical committee for animal study (if any). Kindly consider the manuscript for publication in your journal. I declare that there is no any conflict of Interest for this publication. I also declare that all the authors mentioned in this manuscript have seen the final version of manuscript. I accept all the terms and conditions displayed i