Determination of Regional Bone Blood Flow by Means of Fluorescent Microspheres Using an Automated Sample-Processing Procedure

Accessible online at: www.karger.com/esr Key Words Bone blood flow W Fluorescent microspheres W Animal experiments The determination of regional blood flow utilizing fluo-rescent microspheres (FMs) is an established method for numerous organs. Recent progress, in particular the automation of sample processing, has further improved this method. However, the FM method (reference sam-ple technique), which allows repetitive measurement of regional organ blood flow, has so far not been used for the determination of blood flow in bone. The aim of the present study was to establish FM for the quantificatio