REVIEW PAPER OPEN ACCESS Recent trends in typhoid research- A Review

Typhoid fever is an infectious disease caused by salmonella enterica serotype typhi. It is a disease of global distribution. In India and Bangladesh, the highest incidence has been observed among children aged less than five years, while in Vietnam, the peak incidence has been found to occur in children in between five to nine years. Prevention is the present requirement for the people of this young age group. This article is totally based on literature survey and is the updated work of the published review article of the corresponding author. This article discusses and summarizes important work in literature in response to the epidemiology, symptoms and diagnosis of typhoid. Much stress has been given to salmonella and immune system and study was done on infection of salmonella to various organs. Genes involved during infection and typhoid related to nanotechnology was also described in detail. In this communication the authors reviewed the vaccination used against typhoid fever. Much focused has been given for the plants products and herbal drugs to minimize pathogenicity caused by salmonellae. This article will be very helpful for those researchers working in the field of infectious diseases caused by salmonellae species