Abstract—There is a continuous pressure to make healthcare processes more efficient and effective without sacrificing quality. Conformance checking can be used to improve processes by analyzing event data and directly relating observed behavior and modeled behavior. Conformance checking provides diagnostics that go far beyond measuring traditional key performance indicators. However, current conformance checking techniques focus on a rather simplistic setting where executions of process instances are sequential and homogeneous whereas healthcare processes are known to be dynamic, complex, and ad-hoc. In healthcare process instances of patients often follow a unique path through the process with one-of-a-kind deviations. Moreover, timestamps...