Article Abnormal Functional Activation and Maturation of Fronto-Striato-Temporal and Cerebellar Regions During Sustained Attention in Autism Spectrum Disorder

are common in people with autism spec-trum disorder (ASD) and may have sig-nificant implications for the diagnosis and management of ASD and associated comorbidities. Furthermore, ASD has been associated with atypical structural brain development. The authors used functional MRI to investigate the functional brain maturation of attention between child-hood and adulthood in people with ASD. Method: Using a parametrically modu-lated sustained attention/vigilance task, the authors examined brain activation and its linear correlation with age between childhood and adulthood in 46 health