PURIFICATION, CRYSTALLIZATION AND INITIAL STRUCTURAL SOLUTION OF A NEW-LIKE TOXIN WITH CARDIAC TOXICITY FROM SCORPION BUTHUS MARTENSII

specific toxins, which are composed of 60-72 amino acids in length cross-linked by 4 disulfide bridges, have been divided into two main groups, a toxins and b toxins [2], according to their pharmacological effects on Na+ currents in electrophysiological preparations and their binding properties. The major effect of a toxins is to slow or inhibi