The skin is a large and complex organ that acts as a critical barrier protecting the body from pathogens in the environment. Numerous heterogeneous populations of immune cells are found within skin, including some that remain resident and others that can enter and exit the skin as part of their migration program. Pathogen-specific CD8+ T cells that persist in the epidermis following infection are a unique population of memory cells with important roles in immune surveillance and protective responses to reinfection. How these tissue-resident memory T cells form in the skin, the signals controlling their persistence and behavior, and the mechanisms by which they mediate local recall responses are just beginning to be elucidated. Here, we disc...
The skin represents a specialized site for immune surveillance consisting of resident, inflammatory ...
Resident memory CD8+ T cells (CD8+ TRM) play a central role in tissue immunity. This thesis focusses...
During the last 10 years, a population of clonally expanded T cells that take up permanent residence...
The skin is a large and complex organ that acts as a critical barrier protecting the body from patho...
The cutaneous surface of a normal adult individual contains approximately 20 billion T cells, nearly...
Protective T cell memory has long been thought to reside in blood and lymph nodes, but very recently...
Copyright © 2015, American Association for the Advancement of Science.The skin of an adult human con...
CD4+ T cells orchestrate the recruitment and subsequent activation of innate and adaptive immune cel...
In health, the non-recirculating nature and long-term persistence of tissue-resident memory T cells ...
Abstract: Skin infiltration of circulating memory T cells with cutaneous tropism is considered one o...
A population of memory T cells stay resident (TRM) at all times in peripheral tissues, such as the s...
Activated T lymphocytes give rise to daughter cells that can persist for decades in our body, while ...
International audienceThe human skin is known to be inhabited by diverse microbes, including bacteri...
# The Author(s) 2013. This article is published with open access at Springerlink.com Abstract The sk...
Our immune system has evolved over the years to endow us with optimal protection against a wide rang...
The skin represents a specialized site for immune surveillance consisting of resident, inflammatory ...
Resident memory CD8+ T cells (CD8+ TRM) play a central role in tissue immunity. This thesis focusses...
During the last 10 years, a population of clonally expanded T cells that take up permanent residence...
The skin is a large and complex organ that acts as a critical barrier protecting the body from patho...
The cutaneous surface of a normal adult individual contains approximately 20 billion T cells, nearly...
Protective T cell memory has long been thought to reside in blood and lymph nodes, but very recently...
Copyright © 2015, American Association for the Advancement of Science.The skin of an adult human con...
CD4+ T cells orchestrate the recruitment and subsequent activation of innate and adaptive immune cel...
In health, the non-recirculating nature and long-term persistence of tissue-resident memory T cells ...
Abstract: Skin infiltration of circulating memory T cells with cutaneous tropism is considered one o...
A population of memory T cells stay resident (TRM) at all times in peripheral tissues, such as the s...
Activated T lymphocytes give rise to daughter cells that can persist for decades in our body, while ...
International audienceThe human skin is known to be inhabited by diverse microbes, including bacteri...
# The Author(s) 2013. This article is published with open access at Springerlink.com Abstract The sk...
Our immune system has evolved over the years to endow us with optimal protection against a wide rang...
The skin represents a specialized site for immune surveillance consisting of resident, inflammatory ...
Resident memory CD8+ T cells (CD8+ TRM) play a central role in tissue immunity. This thesis focusses...
During the last 10 years, a population of clonally expanded T cells that take up permanent residence...