Photodynamic Therapy of Prostate Cancer by Means of 5-Aminolevulinic Acid-Induced Protoporphyrin IX – In vivo Experiments on the Dunning Rat Tumor Model

Accessible online at: www.karger.com/uin D.Z. and R.S. contributed equally to the project and are to be consid-ered as co-first authors. This article contains parts of the inaugural thesis of M.H. at Ludwig Maximilians University, Munich. Key Words Photodynamic therapy W Prostate cancer W 5-Aminolevulinic acid Objective: In order to expand the use of photodynamic therapy (PDT) in the treatment of prostate carcinoma (PCA), the aim of this study was to evaluate PDT by means of 5-aminolevulinic acid (5-ALA)-induced proto-porphyrin IX (PPIX) in an in vivo tumor model. Methods