Eccentric Lamellar Keratolimbal Grafts Harvested with a Manually Guided Microkeratome

and a large corneal portion. No visible damage to the limbal region was discernible. Conclusion: Our data show that the LSK-One microkeratome in conjunction with the ALTK sys-tem allows harvesting eccentric keratolimbal grafts from do-nor corneoscleral buttons. Copyright © 2007 S. Karger AG, Basel Limbal stem cells are the ultimate source of corneal epithelial regeneration and are exclusively located at the corneal-conjunctival junction, i.e. the limbus [1–6]. De-struction of the limbal epithelium leads to conjunctival overgrowth (conjunctivalization) on the clear cornea, a condition termed limbal stem cell deficiency (LSCD) [7– 11]. The conventional therapy in this situation is trans-plantation of healthy limbal epithelium to ensure a trans-parent and smooth corneal surface [12–16]. In situations where corneal scarring requires additional lamellar cor-neal transplantation, Sundmacher and Reinhard [17] proposed a technique called lamellar central limbokera-toplasty. Freehand donor limbal tissue harvest is time consum-ing, creates a relatively irregular stromal interface and requires some experience to prevent traumatic alteration Key Word