Availability of a novel criterion for peritoneal diffusive selectivity on peritoneal dialysis

Abstract — In the peritoneal dialysis, it is well-known that the peritoneal permeability increases gradually over the dura-tion of treatment. The enhancement of the peritoneal perme-ability causes an under-dialysis and ultrafiltration failure, which is one of the grave factors which disrupt the homeostasis of body fluid. Hence, the monitoring of the peritoneal perme-ability is very important in order to give each patient some better prescriptions. In this study, we designed a novel crite-rion which can evaluate quantitatively the peritoneal perme-ability by applying a kinetic model for the peritoneal dialysis. Moreover clinical implementations of the novel criterion were validated with using the clinical data. By employing PD NAVI (JMS Co.,Ltd., Hiroshima, Japan), 50 well-being peritoneal dialysis patients performed the peritoneal function test includ-ing the peritoneal equilibration test (PET), which measure