Automated Classification of Cerebral Arteries in MRA Images and Its Application to Maximum Intensity Projection

Abstract — Detection of unruptured aneurysms is a major task in magnetic resonance angiography (MRA). However, it is difficult for radiologists to detect small aneurysms on the maximum intensity projection (MIP) images because adjacent vessels may overlap with the aneurysms. Therefore, we proposed a method for making a new MIP image, the SelMIP image, with the interested vessels only, as opposed to all vessels, by manually selecting a cerebral artery from a list of cerebral arteries recognized automatically. By using our new SelMIP viewing technique, the selected vessel regions can also be observed from various directions and would further facilitate the radiologists in detecting small aneurysms. For automated classification of cerebral arteries, two 3D images, a target image and a reference image, are compared. Image registration is performed using the global matching and feature correspondence techniques. Segmentation of vessels in the target image is performed using the thresholding and region growing techniques. The segmented vessel regions were classified into eight cerebral arteries by calculating the Euclidean distance between a voxel in the target image and each of the voxels in the labeled eight vessel regions in the reference image. In applying the automated cerebral arteries recognization algorithm to thirteen MRA studies, results of 10 MRA studies were evaluated as clinically acceptable. Our new viewing technique would be useful in assisting radiologists for detection of aneurysms and for reducing the interpretation time