Add to ORKGAcquired drug resistance is a major limitation for the successful treatment of cancer. Evolutionary theory has contributed to understanding the dynamics of drug resistance in cancer. We review recent advances in evolutionary models of resistance in cancer. We outline how evolutionary thinking can contribute to outstanding questions in the field. a r t i c l e i n f o Article history
Since the mid 1970s, cancer has been described as a process of Darwinian evolution, with somatic cel...
The design of cancer chemotherapy has become increasingly sophisticated, yet there is no cancer trea...
Rapid evolution is ubiquitous in nature. We briefly review some of this quite broadly, particularly ...
Targeted therapies have revolutionized cancer treatment. Unfortunately, their success is limited due...
<p>An evolutionary view of cancer reveals that therapy selects for resistant cells among an initiall...
Evolutionary theory of cancer was developed in 1976 by cancer research Peter Nowell and has illumina...
In this paper, a model is presented that explores the role of drug resistance in the evolution of ca...
Abstract: Acquired drug resistance is a major limitation for successful treatment of cancer. Resista...
International audienceThe question of a mathematical representation and theoretical overcoming by op...
Theoretical and empirical work over the past several decades suggests that oncogenesis and disease p...
This article is a proceeding survey (deepening a talk given by the first author at the Biomath 2019 ...
International audienceSince the mid 1970s, cancer has been described as a process of Darwinian evolu...
Cancer is a somatic evolutionary process characterized by the accumulation of mutations, which contr...
Theoretical and empirical work over the past several decades suggests that oncogenesis and disease p...
abstract: Cancer therapy selects for cancer cells resistant to treatment, a process that is fundamen...
Since the mid 1970s, cancer has been described as a process of Darwinian evolution, with somatic cel...
The design of cancer chemotherapy has become increasingly sophisticated, yet there is no cancer trea...
Rapid evolution is ubiquitous in nature. We briefly review some of this quite broadly, particularly ...
Targeted therapies have revolutionized cancer treatment. Unfortunately, their success is limited due...
<p>An evolutionary view of cancer reveals that therapy selects for resistant cells among an initiall...
Evolutionary theory of cancer was developed in 1976 by cancer research Peter Nowell and has illumina...
In this paper, a model is presented that explores the role of drug resistance in the evolution of ca...
Abstract: Acquired drug resistance is a major limitation for successful treatment of cancer. Resista...
International audienceThe question of a mathematical representation and theoretical overcoming by op...
Theoretical and empirical work over the past several decades suggests that oncogenesis and disease p...
This article is a proceeding survey (deepening a talk given by the first author at the Biomath 2019 ...
International audienceSince the mid 1970s, cancer has been described as a process of Darwinian evolu...
Cancer is a somatic evolutionary process characterized by the accumulation of mutations, which contr...
Theoretical and empirical work over the past several decades suggests that oncogenesis and disease p...
abstract: Cancer therapy selects for cancer cells resistant to treatment, a process that is fundamen...
Since the mid 1970s, cancer has been described as a process of Darwinian evolution, with somatic cel...
The design of cancer chemotherapy has become increasingly sophisticated, yet there is no cancer trea...
Rapid evolution is ubiquitous in nature. We briefly review some of this quite broadly, particularly ...