To the Editor: Psychiatric symptoms

have been reported, although rarely, among the presenting symptoms of multiple sclerosis (MS). The case presented here refers to a 46-year-old man with no previous psychiatric history, who, immediately after MS diagnosis, manifested delusional ideas of jealousy, illustrating the collaboration of psychosocial and biological factors—with the former probably representing a trigger—in the development of a mental disor-der on the grounds of organic brain disease. Of note, the patient’s symp-toms had remained refractory t