I hereby declare that this thesis is my own work. Under the guidance of my supervisor, Dr Deborah Watson-Jones and the advisory committee (Professors David Mabey and David Ross and Dr Helen Weiss), I wrote the proposal and designed the data collection tools used in this research. I trained the research assistants who particlpated in the data collection and supervised all aspects of data collection. I participated in the data collection: interviewing health workers, interviewing women, recruiting and following up HIV-positive women in the cohort study. I carried out the observational study at the ANC facilities. I prepared the data entry screens, supervised the data entry process and I carried out the data cleaning. I did the data statistica...