RESEARCH Omega-3 fatty acids, poly e R

Full list of author information is available at the end of the articleBackground The lifestyle of the Inuit is rapidly changing towards an increased cardiovascular (CVD) risk factor profile [1]. The CVD risk factors include non-modifiable risk fac-tors such as age, male sex, family history, and modifiable risk factors for example smoking, hypertension, diabetes, and hyperlipidemia. Specifically, improving plasma lipids profile – including: total cholesterol (TC), triacylglycerol (TG), low-density-lipoprotein cholesterol (LDL-C), apo-lipoprotein (apo) B concentrations, apo A1 concentra-tions and high-density-lipoprotein cholesterol (HDL-C)-is associated with a decreased CVD risk [2]. Studies have shown that both environmental and genetic factors may play a role in determining susceptibility to dyslipidemia. The consumption of fish and marine mammals rich in n-3 PUFAs represents an important dietary component for CVD risk prevention in the Inuit population [3]. A high intake of n-3 polyunsaturated fatty acids (n-