Add to ORKGligands trigger at least three different intracellular signaling cascades: the canonical Wnt pathway, which results in The phosphorylated β-catenin becomes ubiquitylated and is targeted for degradation by proteasome. Following Yan et al. Molecular Cancer 2013, 12:11
NoWnt signaling normally functions in cell determination and proliferation and is essential for embr...
The Wnt/β-catenin signaling pathway plays a critical role in embryonic development as well as in the...
WNT signalling is an essential signalling pathway for all multicellular animals. Although first desc...
The control of β-catenin levels is vital to the cell. The primary means of regulation is through ubi...
WNT/β-catenin signaling is a highly complex pathway that plays diverse roles in various cellular pro...
The wnt signal transduction pathway is involved in many differentiation events during embryonic deve...
Figure 1. Canonical Wnt/β-catenin signaling pathway. Wnt ligands are secreted into the extracellular...
The β-catenin destruction complex is a dynamic cytosolic multiprotein assembly that provides a key n...
Abstract: Wnt proteins are a large family of secreted glycoproteins. Wnt proteins bind to the Frizzl...
Mutations in components of the Wnt pathways are a frequent cause of many human diseases, particularl...
Wnt signalling is involved in a variety of mammalian developmental processes, including cell prolife...
<div><p>Aberrant accumulation of intracellular β-catenin is a well recognized characteristic of seve...
Abstract Wnt/β-catenin signaling has been broadly implicated in human cancers and experimental cance...
Abstract Wnt/β-catenin signaling, a highly conserved pathway through evolution, regulates key cellul...
Degradation of cytosolic β-catenin by the APC/Axin1 destruction complex represents the key regulated...
NoWnt signaling normally functions in cell determination and proliferation and is essential for embr...
The Wnt/β-catenin signaling pathway plays a critical role in embryonic development as well as in the...
WNT signalling is an essential signalling pathway for all multicellular animals. Although first desc...
The control of β-catenin levels is vital to the cell. The primary means of regulation is through ubi...
WNT/β-catenin signaling is a highly complex pathway that plays diverse roles in various cellular pro...
The wnt signal transduction pathway is involved in many differentiation events during embryonic deve...
Figure 1. Canonical Wnt/β-catenin signaling pathway. Wnt ligands are secreted into the extracellular...
The β-catenin destruction complex is a dynamic cytosolic multiprotein assembly that provides a key n...
Abstract: Wnt proteins are a large family of secreted glycoproteins. Wnt proteins bind to the Frizzl...
Mutations in components of the Wnt pathways are a frequent cause of many human diseases, particularl...
Wnt signalling is involved in a variety of mammalian developmental processes, including cell prolife...
<div><p>Aberrant accumulation of intracellular β-catenin is a well recognized characteristic of seve...
Abstract Wnt/β-catenin signaling has been broadly implicated in human cancers and experimental cance...
Abstract Wnt/β-catenin signaling, a highly conserved pathway through evolution, regulates key cellul...
Degradation of cytosolic β-catenin by the APC/Axin1 destruction complex represents the key regulated...
NoWnt signaling normally functions in cell determination and proliferation and is essential for embr...
The Wnt/β-catenin signaling pathway plays a critical role in embryonic development as well as in the...
WNT signalling is an essential signalling pathway for all multicellular animals. Although first desc...