Abstract: The interleukin 28B (IL28B) rs12979860 polymorphism is associated with treatment outcome in hepatitis C virus (HCV) genotype 1 and 4 patients. Its association with the histological features of chronic hepatitis C and disease severity needs further clarifications. To assess the correlation between IL28B genotype, HCV genotype and liver biopsy findings in untreated patients. Materials and Methods: Pre-treatment liver biopsies from 335 HCV Caucasian patients (59 % males, age 50 years) enrolled in the MIST study were staged for fibrosis and inflammation according to the METAVIR and the Ishak scoring systems; steatosis was dichotomized as <5 % or ≥5%. IL28B was typed by Taqma
BACKGROUND & AIMS: Genetic variation in the interleukin 28B (IL28B) gene has been associated wit...
Three landmark genome-wide association studies (GWAS) published in 2009 identified the interleukin (...
Background and Aims: Recently, several genome-wide association studies have revealed that single nuc...
The interleukin 28B (IL28B) rs12979860 polymorphism is associated with treatment outcome in hepatiti...
The interleukin 28B (IL28B) rs12979860 polymorphism is associated with treatment outcome in hepatiti...
Background and purpose: Contradictory data exist on the association between host interleukin-28B (IL...
Background and Aims: Recently, several genome-wide association studies have revealed that single nuc...
Copyright © 2015 Ahmed Al-Qahtani et al. This is an open access article distributed under the Creati...
BACKGROUND/AIMS: Polymorphism at the IL28B gene may modify the course of hepatitis C virus (HCV) chr...
BACKGROUND: This study aimed to determine whether the single-nucleotide polymorphism (rs12979860 C/...
Background and Aim: While genetic polymorphisms upstream of the interleukin-28B (IL28B) gene are ass...
Recently, several genome-wide association studies have revealed that single nucleotide polymorphisms...
Background: Host genetic factors can affect the progress of hepatitis-C virus (HCV) infection. Inter...
Recent studies have demonstrated that polymorphisms near the interleukin-28B (IL-28B) gene could pre...
With the aim of investigating whether interleukin 28B gene (IL28B) rs1297860 polymorphism is associa...
BACKGROUND & AIMS: Genetic variation in the interleukin 28B (IL28B) gene has been associated wit...
Three landmark genome-wide association studies (GWAS) published in 2009 identified the interleukin (...
Background and Aims: Recently, several genome-wide association studies have revealed that single nuc...
The interleukin 28B (IL28B) rs12979860 polymorphism is associated with treatment outcome in hepatiti...
The interleukin 28B (IL28B) rs12979860 polymorphism is associated with treatment outcome in hepatiti...
Background and purpose: Contradictory data exist on the association between host interleukin-28B (IL...
Background and Aims: Recently, several genome-wide association studies have revealed that single nuc...
Copyright © 2015 Ahmed Al-Qahtani et al. This is an open access article distributed under the Creati...
BACKGROUND/AIMS: Polymorphism at the IL28B gene may modify the course of hepatitis C virus (HCV) chr...
BACKGROUND: This study aimed to determine whether the single-nucleotide polymorphism (rs12979860 C/...
Background and Aim: While genetic polymorphisms upstream of the interleukin-28B (IL28B) gene are ass...
Recently, several genome-wide association studies have revealed that single nucleotide polymorphisms...
Background: Host genetic factors can affect the progress of hepatitis-C virus (HCV) infection. Inter...
Recent studies have demonstrated that polymorphisms near the interleukin-28B (IL-28B) gene could pre...
With the aim of investigating whether interleukin 28B gene (IL28B) rs1297860 polymorphism is associa...
BACKGROUND & AIMS: Genetic variation in the interleukin 28B (IL28B) gene has been associated wit...
Three landmark genome-wide association studies (GWAS) published in 2009 identified the interleukin (...
Background and Aims: Recently, several genome-wide association studies have revealed that single nuc...