INTENDED USE The BBL ™ MGIT ™ Mycobacteria Growth Indicator Tube supplemented with BACTEC ™ MGIT ™ Growth Supplement and BBL ™ MGIT™

PANTA ™ antibiotic mixture is intended for the detection and recovery of mycobacteria using the BACTEC ™ MGIT ™ 960 and BACTEC ™ MGIT™ 320 Systems. Acceptable specimen types are digested and decontaminated clinical specimens (except urine), and sterile body fluids (except blood). SUMMARY AND EXPLANATION From 1985 to 1992, the number of reported cases of infection with Mycobacterium tuberculosis (MTB) increased 18%. Tuberculosis still kills an estimated 3 million persons a year worldwide, making it the leading infectious disease cause of death.1 Between 1981 and 1987, AIDS case surveillances indicated that 5.5 % of the patients with AIDS had disseminated nontuberculous mycobacterial infections; e.g., MAC. By 1990, the increased cases of disseminated nontuberculous mycobacterial infections had resulted in a cumulative incidence of 7.6%.2 In addition to th