Evaluation of Stability study of Selected Preservatives in

Plan: The aim of present study is to find out new preservatives synthesized from natural sources, which may have better efficiency and stability than the existing synthetic preservatives. The derivatives of naturally occurring gallic, p-coumaric and ferulic acids were subjected to pharmaceutical product for their stability study. Their preservative efficiency was evaluated and compared with the standard parabens. Preface: Deterioration of pharmaceutical preparations due to growth of microorganisms is a great challenge and need of preservation becomes very important. Literature reports about various problems associated with the existing synthetic preservatives such as lack of stability, development of microbial resistance (in due course of time) and several serious side effects