Add to ORKGNonalcoholic fatty liver disease (NAFLD) is highly prevalent and can result in nonalcoholic steatohepatitis (NASH) and progressive liver disease including cirrhosis and hepatocellular carcinoma. A growing body of literature implicates the peroxisome proliferators-activated receptors (PPARs) in the pathogenesis and treatment of NAFLD. These nuclear hormone receptors impact on hepatic triglyceride accumulation and insulin resistance. The aim of this review is to describe the data linking PPARα and PPARγ to NAFLD/NASH and to discuss the use of PPAR ligands for the treatment of NASH. © 2008 WJG. All rights reserved. Key words: Non-alcoholic fatty liver disease; Peroxisome proliferators-activated receptors; Insulin resiatance
Non-alcoholic fatty liver disease (NAFLD) is a major health issue in developed countries. Although u...
Non-alcoholic fatty liver disease (NAFLD) is a liver pathology with increasing prevalence due to the...
International audiencePeroxisome proliferator-activated receptors (PPAR), ligand-activated transcrip...
Non-alcoholic fatty liver disease (NAFLD) is a major health issue in developed countries. Although u...
Non-alcoholic fatty liver disease (NAFLD) is a major health issue in developed countries. Although u...
International audienceNon-alcoholic fatty liver disease (NAFLD) is a major health issue in developed...
International audienceNon-alcoholic fatty liver disease (NAFLD) is a major health issue worldwide, f...
Non-alcoholic fatty liver disease (NAFLD) is a liver pathology with increasing prevalence due to the...
Non-alcoholic fatty liver disease (NAFLD) is a liver pathology with increasing prevalence due to the...
Non-alcoholic fatty liver disease (NAFLD) is a liver pathology with increasing prevalence due to the...
Non-alcoholic fatty liver disease (NAFLD) is a liver pathology with increasing prevalence due to the...
Non-alcoholic fatty liver disease (NAFLD) has been defined as a spectrum of histological abnormaliti...
The increasing epidemic of obesity worldwide is linked to serious health effects, including increase...
permits unrestricted use, distribution, and reproduction in any medium, provided the original work i...
Non-alcoholic fatty liver disease (NAFLD) is a major health issue in developed countries. Although u...
Non-alcoholic fatty liver disease (NAFLD) is a major health issue in developed countries. Although u...
Non-alcoholic fatty liver disease (NAFLD) is a liver pathology with increasing prevalence due to the...
International audiencePeroxisome proliferator-activated receptors (PPAR), ligand-activated transcrip...
Non-alcoholic fatty liver disease (NAFLD) is a major health issue in developed countries. Although u...
Non-alcoholic fatty liver disease (NAFLD) is a major health issue in developed countries. Although u...
International audienceNon-alcoholic fatty liver disease (NAFLD) is a major health issue in developed...
International audienceNon-alcoholic fatty liver disease (NAFLD) is a major health issue worldwide, f...
Non-alcoholic fatty liver disease (NAFLD) is a liver pathology with increasing prevalence due to the...
Non-alcoholic fatty liver disease (NAFLD) is a liver pathology with increasing prevalence due to the...
Non-alcoholic fatty liver disease (NAFLD) is a liver pathology with increasing prevalence due to the...
Non-alcoholic fatty liver disease (NAFLD) is a liver pathology with increasing prevalence due to the...
Non-alcoholic fatty liver disease (NAFLD) has been defined as a spectrum of histological abnormaliti...
The increasing epidemic of obesity worldwide is linked to serious health effects, including increase...
permits unrestricted use, distribution, and reproduction in any medium, provided the original work i...
Non-alcoholic fatty liver disease (NAFLD) is a major health issue in developed countries. Although u...
Non-alcoholic fatty liver disease (NAFLD) is a major health issue in developed countries. Although u...
Non-alcoholic fatty liver disease (NAFLD) is a liver pathology with increasing prevalence due to the...
International audiencePeroxisome proliferator-activated receptors (PPAR), ligand-activated transcrip...