Add to ORKGIn the process of cellular carcinogenesis, genetic and epigenetic mechanisms contribute to abnormal expression of genes. Conrad Waddington introduced the term ‘‘epigenetics’ ’ in 1942 (Goldberg, Allis et al. 2007) to describe heritable changes in gene expression that have no connection with changes in DNA sequence (Yoo and Jones 2006; Goldberg, Allis et al
Appropriate patterns of DNA methylation and histone modifications are required to assure cell identi...
Cancer is a disease arising from both genetic and epigenetic modifications of DNA that contribute to...
The genetic information of almost all eukaryotic cells is stored in chromatin. In cancer cells, alte...
In the past, the term epigenetics was used to describe all biological phenomena that do not follow n...
Compared to the normal tissues, cancer cells tend to have higher proliferation rate and often lost t...
Cancer is now thought of as a fundamentally genetic disease, in that changes in the genome result in...
Epigenetic mechanisms are essential for normal development and maintenance of lineage-specific gene ...
Cancer is traditionally viewed as a primarily genetic disorder, however it is now becoming accepted ...
Genetic aberrations, including chromosomal rearrangements, loss or amplification of DNA, and point m...
Since the early 80's, cancer research has been dominated by scientific breakthroughs demonstrating t...
Epigenetic modifications are central to many human diseases, including cancer. Traditionally, cancer...
Epigenetics is the study of heritable changes in gene activities that are not caused by changes in t...
Epigenetics has become a fast-growing area of study in cellular biology. An epigenetic trait is defi...
Epigenetic mechanisms are essential for normal development and maintenance of lineage-specific gene ...
that is mediated by mechanisms other than alterations in the primary nucleotide sequence of a gene.2...
Appropriate patterns of DNA methylation and histone modifications are required to assure cell identi...
Cancer is a disease arising from both genetic and epigenetic modifications of DNA that contribute to...
The genetic information of almost all eukaryotic cells is stored in chromatin. In cancer cells, alte...
In the past, the term epigenetics was used to describe all biological phenomena that do not follow n...
Compared to the normal tissues, cancer cells tend to have higher proliferation rate and often lost t...
Cancer is now thought of as a fundamentally genetic disease, in that changes in the genome result in...
Epigenetic mechanisms are essential for normal development and maintenance of lineage-specific gene ...
Cancer is traditionally viewed as a primarily genetic disorder, however it is now becoming accepted ...
Genetic aberrations, including chromosomal rearrangements, loss or amplification of DNA, and point m...
Since the early 80's, cancer research has been dominated by scientific breakthroughs demonstrating t...
Epigenetic modifications are central to many human diseases, including cancer. Traditionally, cancer...
Epigenetics is the study of heritable changes in gene activities that are not caused by changes in t...
Epigenetics has become a fast-growing area of study in cellular biology. An epigenetic trait is defi...
Epigenetic mechanisms are essential for normal development and maintenance of lineage-specific gene ...
that is mediated by mechanisms other than alterations in the primary nucleotide sequence of a gene.2...
Appropriate patterns of DNA methylation and histone modifications are required to assure cell identi...
Cancer is a disease arising from both genetic and epigenetic modifications of DNA that contribute to...
The genetic information of almost all eukaryotic cells is stored in chromatin. In cancer cells, alte...