A Case of Rare Heterozygous oe.l-Antitrypsin Phenotype: IS

Summary: We describe a case of the heterozygous antitrypsin phenotype IS. The 20 years old female employee had been recurrently suffering from cutaneous vasculitis over a period of three years. Serum trypsin Inhibitor was found to be high (1394 ImU) during the acute stage of the disease. No other serological or physical abnormalities were detected. A relationship between certain Pi (the term Pi indicating protease Inhibitor = OL \-antitrypsin) alleles and vasculitis is possible but not certain, äs three out of four other patients with this disease were MM phenotypes, the other one being MS type. Fall eines seltenen heterozygoten o ^-Antitrypsin-Phänotyps: I