Abnormalities in Erythrocyte Membrane Protein in Pseudohypoparathyroidism Type l1)

Summary: The erythrocyte membrane proteins of patients with pseudohypoparathyroidism type l and healthy volunteers were analysed by two-dimensional polyacrylamide gel electrophoresis in combination with a sensitive silver staining method. Electrophoretograms from patients were invariably different from control separations with respect to at least three protein spots. The possible relationship with the regulatory compo-nent of adenyl cyclase is discussed. Abweichungen im Proteinspektrum der Erythrocytenmembran bei Pseudohypoparathyreoidismus Typ