ORIGINAL ARTICLE ESTHESIONEUROBLASTOMA: THE PRINCESS MARGARET HOSPITAL EXPERIENCE

Abstract: Background. Esthesioneuroblastoma is rare. The aim of the study was to review our experience and to evaluate the staging system and treatment that best correlates with the patient outcome. Methods. Thirty-nine patients were identified between 1972 and 2006. Results. At presentation 10 % had cervical metastases. None had distant metastasis. Five were treated with surgery, 2 with chemotherapy, 1 with radiotherapy, and 30 with surgery and radiation. Local disease control was 82.6 % at 5 years. Recur-rence was seen in 33 % with local and regional disease recur-rence at 15 % and 18%, respectively. The 5- and 10-year overall survival rates were 87.9 % and 69.2%, respectively. Dulguerov classification correlated most closely to survival and recurrence. Conclusions. Dulguerov classification best correlates with th