Purpose: Despite the increasing concern about the effect of doses below 0.5 Gy and non-targeted exposures of ionising radiation on living organisms, the majority of radiobiological studies are conducted using in vitro cell lines. In order to be able to extrapolate the in vitro results to in vivo models with confidence, it would be of great benefit to develop a reproducible tissue system suitable for critical radiobiological assays. This manuscript describes the development of a reliable protocol to harvest cells from tissue samples and investigate the radiation damage induced on a single cell basis. Materials and methods: To validate this approach as a potential tool for bystander experiments, the method focuses on analysing radiation damag...
International audienceThe objective of this work was to study the differences in terms of early biol...
Microbeams are ideally suited to the study of so-called 'non-targeted' phenomena that are now known ...
Purpose: To establish stable in vitro growth of keratinocytes from very small biopsy specimens and s...
Purpose: Despite the increasing concern about the effect of doses below 0.5 Gy and non-targeted expo...
The universality of the target theory of radiation-induced effects is challenged by observations of ...
Low linear energy transfer (LET) ionizing radiation as gamma and X-rays is widely used in the modem ...
Ionising radiation can produce a number of effects in living cells and organisms. One way to investi...
The management of the risks of exposure of people to ionizing radiation is important in relation to ...
The management of the risks of exposure of people to ionizing radiation is important in relation to ...
It is now accepted that biological effects may occur in cells that were not themselves traversed by ...
Three different biological extremes of irradiation of living organisms, both human and animal, have ...
Knowledge of cellular responses in tissue microenvironment is crucial for the accurate prediction of...
International audienceThe objective of this work was to study the differences in terms of early biol...
International audienceThe objective of this work was to study the differences in terms of early biol...
Microbeams are ideally suited to the study of so-called 'non-targeted' phenomena that are now known ...
International audienceThe objective of this work was to study the differences in terms of early biol...
Microbeams are ideally suited to the study of so-called 'non-targeted' phenomena that are now known ...
Purpose: To establish stable in vitro growth of keratinocytes from very small biopsy specimens and s...
Purpose: Despite the increasing concern about the effect of doses below 0.5 Gy and non-targeted expo...
The universality of the target theory of radiation-induced effects is challenged by observations of ...
Low linear energy transfer (LET) ionizing radiation as gamma and X-rays is widely used in the modem ...
Ionising radiation can produce a number of effects in living cells and organisms. One way to investi...
The management of the risks of exposure of people to ionizing radiation is important in relation to ...
The management of the risks of exposure of people to ionizing radiation is important in relation to ...
It is now accepted that biological effects may occur in cells that were not themselves traversed by ...
Three different biological extremes of irradiation of living organisms, both human and animal, have ...
Knowledge of cellular responses in tissue microenvironment is crucial for the accurate prediction of...
International audienceThe objective of this work was to study the differences in terms of early biol...
International audienceThe objective of this work was to study the differences in terms of early biol...
Microbeams are ideally suited to the study of so-called 'non-targeted' phenomena that are now known ...
International audienceThe objective of this work was to study the differences in terms of early biol...
Microbeams are ideally suited to the study of so-called 'non-targeted' phenomena that are now known ...
Purpose: To establish stable in vitro growth of keratinocytes from very small biopsy specimens and s...