The Effect of Hazel- Leaf Decoction on Blood Glucose Reduction in the Diabetic Rats

Abstract: Regarding the various complications of diabetes, searching for methods and means for its treatment are necessary. Since some people use the hazel- leaf decoction for this purpose, the researchers were motivated to test the effect of it on rats and study its mechanism in the succeeding surveys in case of its efficacy. Fifty mg kg of streptozocin was injected intraperitonaly to 12 rats. Then, they were divided into two groups. The1 experimental group was given 10 % Hazel- leaf decoction and control group was received drinking water. The blood glucose level was measured for both the experimental and control groups on the days: 0, 3, 7, 15 and 30. The research revealed that this decoction given reduced blood glucose from the day 7, 15 and 30 significantly (p<0.007, p<0.001, p<0.001, respectively) as compared to the control group. Key words: Glucose Hazel- leaf diabetic rats INTRODUCTION In 1970, it was reported that long-term use of Diabetes is a chronic and lifetime disease, which is mortality as compared to insulin or placebo [5]. Lactic considered as one of the most important endocrine acidosis is one of the adverse effects of biguanides [6]. disorders. The chief manifestations of DM are Because of several complications of DM and hyperglycemia and fat and protein metabolic disorders. significant adverse effects of hypoglycemic agents