tem ” (RAPS) refers to the pathogenic mechanisms whereby prorenin binding to its receptor dually activates the tissue renin-angiotensin system (RAS) and RAS-independent intra-cellular signaling via the receptor. The aim of the present study was to define the association of the RAPS with diabetes-induced retinal inflammation. RESEARCH DESIGN AND METHODS—Long-Evans rats, C57BL/6 mice, and angiotensin II type 1 receptor (AT1-R)-deficient mice with streptozotocin-induced diabetes were treated with (pro)renin receptor blocker (PRRB). Retinal mRNA expres-sion of prorenin and the (pro)renin receptor was examined by quantitative RT-PCR. Leukocyte adhesion to the retinal vascula-ture was evaluated with a concanavalin A lectin perfusion– labeling tec...
Morbidity and mortality of diabetes mellitus are strongly associated with cardiovascular disease inc...
1. (Pro)renin receptor (PRR) binding to renin or prorenin mediates Ang II dependent and independent ...
The (pro)renin receptor (PRR) binds renin and prorenin, its proenzyme inactive form. Receptor-bound ...
Abstract The renin–angiotensin system (RAS), a crucial regulator of systemic blood pressure (circula...
<div><p>(Pro)renin receptor [(P)RR], a new component of the tissue renin-angiotensin system (RAS), p...
AbstractThe renin–angiotensin system (RAS) plays pivotal roles in homeostasis, but its abnormal acti...
(Pro)renin receptor [(P)RR], a new component of the tissue renin-angiotensin system (RAS), plays a c...
Dysfunction of renin-angiotensin system (RAS) contributes to the pathogenesis of diabetic retinopath...
textabstractDysfunction of renin-angiotensin system (RAS) contributes to the pathogenesis of diabeti...
Dysfunction of renin-angiotensin system (RAS) contributes to the pathogenesis of diabetic retinopath...
The receptor-associated prorenin system (RAPS) re-fers to pathogenic mechanisms whereby prorenin bin...
Dysfunction of renin-angiotensin system (RAS) contributes to the pathogenesis of diabetic retinopath...
Receptor-associated prorenin system (RAPS) refers to the pathogenic mechanism whereby prorenin bindi...
Purpose: Retinopathy of prematurity (ROP) is the main cause of vision loss and blindness in children...
The receptor-associated prorenin system refers to the pathogenic mechanism whereby prorenin binding ...
Morbidity and mortality of diabetes mellitus are strongly associated with cardiovascular disease inc...
1. (Pro)renin receptor (PRR) binding to renin or prorenin mediates Ang II dependent and independent ...
The (pro)renin receptor (PRR) binds renin and prorenin, its proenzyme inactive form. Receptor-bound ...
Abstract The renin–angiotensin system (RAS), a crucial regulator of systemic blood pressure (circula...
<div><p>(Pro)renin receptor [(P)RR], a new component of the tissue renin-angiotensin system (RAS), p...
AbstractThe renin–angiotensin system (RAS) plays pivotal roles in homeostasis, but its abnormal acti...
(Pro)renin receptor [(P)RR], a new component of the tissue renin-angiotensin system (RAS), plays a c...
Dysfunction of renin-angiotensin system (RAS) contributes to the pathogenesis of diabetic retinopath...
textabstractDysfunction of renin-angiotensin system (RAS) contributes to the pathogenesis of diabeti...
Dysfunction of renin-angiotensin system (RAS) contributes to the pathogenesis of diabetic retinopath...
The receptor-associated prorenin system (RAPS) re-fers to pathogenic mechanisms whereby prorenin bin...
Dysfunction of renin-angiotensin system (RAS) contributes to the pathogenesis of diabetic retinopath...
Receptor-associated prorenin system (RAPS) refers to the pathogenic mechanism whereby prorenin bindi...
Purpose: Retinopathy of prematurity (ROP) is the main cause of vision loss and blindness in children...
The receptor-associated prorenin system refers to the pathogenic mechanism whereby prorenin binding ...
Morbidity and mortality of diabetes mellitus are strongly associated with cardiovascular disease inc...
1. (Pro)renin receptor (PRR) binding to renin or prorenin mediates Ang II dependent and independent ...
The (pro)renin receptor (PRR) binds renin and prorenin, its proenzyme inactive form. Receptor-bound ...