Administration of potent mouse interferon preparations or anti-mouse interferon globulin did not influence the evolution of scrapie in mice after intraperitoneal injection of the agent. We conclude that the interferon system is probably not involved in scrapie, The scrapie agent has been considered by many investigators tobe a small virus but its nature is still unknown (Kimberlin, 1982; Prusiner, 1982). It is known that the evolution of most acute virus diseases can be inhibited by interferon (Stewart, 1979) and we have previously attempted to modify the course of scrapie in mice by daily administration of interferon for 3 months (Gresser & Pattison, 1968). In these experiments he scrapie agent was inoculated intracere-brally (i.c.). A...
Euthymic and athymic female BALB/c mice, reared under either germfree or defined flora conditions, w...
The susceptibility of humans and animals to prion infections is determined by the virulence of the i...
The susceptibility of humans and animals to prion infections is determined by the virulence of the i...
Administration of potent mouse interferon preparations or anti-mouse interferon globulin did not inf...
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/73540/1/j.1749-6632.1977.tb22003.x.pd
Using the severe combined immunodeficiency (SCID) mouse model, we investigated the requirement of th...
A single injection of 1 mg dextran sulphate 500 per mouse considerably prolonged incubation times an...
SJL/J mice are resistant, whereas A/WySnJ mice are susceptible to intraperitoneally (i.p.) inoculate...
ABSTRACT-In inbred DBA/2 mice, the antitumor activities of separate and combined preparations of mou...
Lymphocytic choriomeningitis (LCM) viruses isolated from the blood of persistently infected mice, co...
The intracerebral (i.c.) injection of mice with a particular source of hamster passaged scrapie prod...
Previous work has shown that homogenates of brain from mice infected with scrapie contain a factor t...
Suckling Swiss mice were injected daily for 8 days with either electrophoretically pure (EP) mouse i...
The dynamics of scrapie agent replication in brain and spleen following intracerebral orintraperiton...
After intracerebral inoculation of adult C3H mice, the 'docile ' strain of lymphocytic cho...
Euthymic and athymic female BALB/c mice, reared under either germfree or defined flora conditions, w...
The susceptibility of humans and animals to prion infections is determined by the virulence of the i...
The susceptibility of humans and animals to prion infections is determined by the virulence of the i...
Administration of potent mouse interferon preparations or anti-mouse interferon globulin did not inf...
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/73540/1/j.1749-6632.1977.tb22003.x.pd
Using the severe combined immunodeficiency (SCID) mouse model, we investigated the requirement of th...
A single injection of 1 mg dextran sulphate 500 per mouse considerably prolonged incubation times an...
SJL/J mice are resistant, whereas A/WySnJ mice are susceptible to intraperitoneally (i.p.) inoculate...
ABSTRACT-In inbred DBA/2 mice, the antitumor activities of separate and combined preparations of mou...
Lymphocytic choriomeningitis (LCM) viruses isolated from the blood of persistently infected mice, co...
The intracerebral (i.c.) injection of mice with a particular source of hamster passaged scrapie prod...
Previous work has shown that homogenates of brain from mice infected with scrapie contain a factor t...
Suckling Swiss mice were injected daily for 8 days with either electrophoretically pure (EP) mouse i...
The dynamics of scrapie agent replication in brain and spleen following intracerebral orintraperiton...
After intracerebral inoculation of adult C3H mice, the 'docile ' strain of lymphocytic cho...
Euthymic and athymic female BALB/c mice, reared under either germfree or defined flora conditions, w...
The susceptibility of humans and animals to prion infections is determined by the virulence of the i...
The susceptibility of humans and animals to prion infections is determined by the virulence of the i...