Transfusion Medicine

Donation of hematopoietic stem cells, either through bone marrow or peripheral blood collection, is a generally safe procedure for healthy donors. Serious adverse events are uncommon and death is exceed-ingly rare. Nevertheless, all donors must be carefully evaluated and fully informed prior to donation. This should be done by clinicians having good understand-ing of the potential physical and psychological compli-cations of donation and the factors that may increase these risks. Additionally, donors and graft products must be evaluated for the potential to transmit infec-tions and other diseases to the recipient and to satisfy an increasing number of national and international regulatory requirements. Donors must be able to provide informed consent without coercion or pres