The Turkish Journal of Pediatrics 2005; 47: 173-175 Case Chronic hereditary pancreatitis with N29I mutation in a Turkish child

Hereditary pancreatitis, an autosomal dominant disease, is the second most common cause of pancreatitis in children. Here we report a child with recurrent pancreatitis attacks and N29I mutation. Due to the increased risk of pancreatic cancer, taking a detailed past and family history and early diagnosis are important. Key words: hereditary pancreatitis, N29I mutation, endoscopic retrograde cholangiopancreatography. Hereditary pancreatitis (HP) is an autosomal dominant disorder characterized by recurrent episodes of acute pancreatitis during childhood. It is the second most common cause of chronic pancreatitis in children1. Recurrent attacks frequently progress to chronic pancreatitis and subsequent pancreatic ductal adenocarcinoma in time. Since the incidence of pancreatic ancer is 53-fold increased over the general populatio