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This paper discusses the current approach taken to implementing the Study Data Tabulation Model (SDTM) version 1.0 at the Duke Clinical Research Institute (DCRI). Possible routes to SDTM implementation are explored. The challenges of the DCRI SDTM implementation are discussed. Finally, some generic SDTM SAS ® conversion macros are provided. The SAS code provided in this paper was developed with BASE SAS version 8.2 on UNIX, but the code should be compatible or portable to other operating systems and future releases of SAS. This paper assumes that the reader has some familiarity with the CDISC models and in particular the SDTM